Castration

PART IV: WELFARE IMPLICATIONS OF CURRENT METHODS OF CASTRATION AND TAIL DOCKING Castration by elastration (the rubber ring method) Short scrotum castration Immunocastration Surgical castration Clamp (bloodless) castration

Castration-resistant Prostate CanCer

• Objective: To review therapeutics for castrationresistant prostate cancer (CRPC). • Methods: Literature review. • Results: Targeting of androgen-dependent pathways in CRPC post-chemotherapy has been shown to improve survival with the lyase inhibitor abiraterone and lead to PSA and objective responses with an androgen receptor antagonist (MDV3100). However, the addition of bevacizumab to docet...

Single Orbital Metastasis in Castration-Resistant Prostate Cancer

Introduction: Orbital metastasis of prostate cancer (PC) is very rare and even more unique in castration-resistant PC (CRPC). In this scenario, choline positron emission tomography/computed tomography (choline PET/CT) is the gold-standard restaging method of choice available in our setting, and new anti-androgens treatments show improvement in overall survival. Case presentation: We report the...

Single Orbital Metastasis in Castration-Resistant Prostate Cancer

Introduction: Orbital metastasis of prostate cancer (PC) is very rare and even more unique in castration-resistant PC (CRPC). In this scenario, choline positron emission tomography/computed tomography (choline PET/CT) is the gold-standard restaging method of choice available in our setting, and new anti-androgens treatments show improvement in overall survival. Case presentation: We report the...

Self-castration: a case report

We present a case of an apparently well gentleman performing self-castration. On presentation he was in shock. After resuscitation his wound was explored and haemostasis achieved. While such presentations are seen with a background of psychiatric illness, our patient did not suffer from such disorders. This case emphasises the importance of a multi-disciplinary holistic approach for optimum pat...